Antibiotic resistance

Both the NHS and health organisations across the world are trying to reduce the use of antibiotics, especially for conditions that are not serious.

This is to try to combat the problem of antibiotic resistance, which is when a strain of bacteria no longer responds to treatment with one or more types of antibiotics.

Antibiotic resistance can occur in several ways. Strains of bacteria can change (mutate) and, over time, become resistant to a specific antibiotic. The chance of this increases if a person does not finish the course of antibiotics they have been prescribed, as some bacteria may be left to develop resistance.

Antibiotics can also destroy many of the harmless strains of bacteria that live in and on the body. This allows resistant bacteria to multiply quickly and replace them.

The overuse of antibiotics in recent years has played a major part in antibiotic resistance. This includes using antibiotics to treat minor conditions that would have got better anyway.

It has led to the emergence of “superbugs”. These are strains of bacteria that have developed resistance to many different types of antibiotics.

They include:

  • meticillin-resistant Staphylococcus aureus (MRSA)
  • Clostridium difficile (C. diff)
  • Bacteria that cause multi-drug-resistant tuberculosis (MDR-TB)
  • Carbapenemase-producing Enterobacteriaceae (CPE)

These types of infections can be serious and challenging to treat, and are becoming an increasing cause of disability and death across the world. The World Health Organization (WHO) estimates there are around 170,000 deaths related to MDR-TB each year.

The biggest worry is new strains of bacteria may emerge that cannot be effectively treated by any existing antibiotics.

Carbapenemase-producing Enterobacteriaceae are one such emerging group of bacteria, with several types. These bacteria are widespread in some parts of the world, including parts of Europe, and are beginning to be seen in the UK.